Seven years ago, a meteorite struck the Shibuya district of Tokyo. Alien lifeforms known as the Worms, emerged from the meteorite and became a threat to humanity. Ever since, Souji Tendou has been training while waiting for the Kabuto Zecter so that he may properly take up the mantle of Kamen Rider Kabuto. Making many enemies while at the same time meeting other Riders with mysterious origins, Tendou attempts to accomplish his goal at all costs: to destroy all Worms that threaten humanity.